Clinical research

【Treatment of diabetic nephropathy】:

The researchers used a streptozotocin (STZ)-induced diabetic rat as animal model. The treatment of Chinese herbs was mainly to give the feed of Arctium lappa, the extract of Arctiin, and alcohol extracts for 6 weeks. In the experiment, the general condition of rats and changes in urine protein, urinary microalbumin, and renal function were observed, and it was found that the extract of Arctium lappa can significantly improve the symptoms of multiple drinking, eating and wasting in STZ rats.

It was found that MCP-1 is the most important cytokine that infiltrate tissue in monocytes and is the chemokine that mainly chemotizes and activates macrophages. The study suggests that the infiltration of monocytes in monocytes is associated with the accumulation of extracellular matrix and the development of glomerulosclerosis. Rovin et al. showed that DN-1 can synthesize MCP-1 in the kidney, and MCP-1 and kidneys are small. Ball injury related.

Experimental and clinical studies have shown that the expression of TGFp1 mRNA and protein in the biopsy tissue of diabetic rats and diabetic nephropathy were significantly increased, with renal hypertrophy and extracellular matrix hyperplasia.

The results of the experiment show that each drug group can reduce the expression of TGF-pl mRNA, and there is a significant difference from the model group; the treatment group of burdock fruit alcohol and the water extract group of burdock fruit have no other compared with the normal group. The difference in significance is greater than that of the burdock meal group. Through experiments proved that it can prevent and treat diabetic nephropathy.

[to effect the defecation:]

From the analysis of the savory taste effect of Arctium lappa, the defecation mechanism mainly involves the following three aspects. The first is to intestine. Burdock seeds are the seeds of burdock, rich in oil, and more slippery. Modern pharmacological studies have shown that the main components of burdock are burdock and fatty oil, and these ingredients have the function of laxative. Clinical experience, burdock hard hard-sliding, slippery patency role in the strong, so patients with constipation, homes Huang, Glauber's salt, hemp benevolence, and individually re-use burdock 24g, implying this idea. Second, lower lung. The air of the lungs is the same as the large intestine. The passage of bowels depends on the deterrence of the lungs. If the lung loses its vitality, the large intestine will not be able to push it. Therefore, we must first cure the lungs. Burdock into the lungs, can breathe. Such as Zhang Xichun: "The calf son can descend the lung's inverse" "Suzi, calf can clear the evil spirits and fall, reverse the gas and turn down" ("Medical Center for Participation in Western Record"). With its laxative, there is a "to mention the pot uncovered" wonderful. Third, lower stomach. Stomach down the food residue under the large intestine, and then become excreted in the stool. Niu Zizi enters the stomach, "Since the bitter drop, the force of the downside is more" ("Materia Medica justice"), can lower the stomach, there is the role of gastric motor drugs. Such as Zhang Xichun: "...then it is with the medicine of descending stomach, the stone in the square, orange peel, burdock is also" ("Medical Center for Participation in Western Records"). In short, burdock is cold and tastes hard. Cold heat, bitter diarrhea, Xinneng line, apply to a variety of heat poison Tianjin constipation. Such as "Drugification of justice," the cloud: "The calf son can rise or fall, solve the toxic heat, taste bitter to clear the fire, with Xinnong Shufeng, attending ... ... all kinds of drug enthusiasm ..."

[Treatment of synovitis]:

Niuqianzi Decoction for the Treatment of Spleen Deficiency and Dampness Knee Osteoarthritis Synovitis: Knee osteoarthritis occurs mostly in the elderly or is caused by non-inflammatory degenerative changes of articular cartilage due to other causes, and has osteophyte formation at the edge of the joint. It can cause joint pain, limited mobility, and joint deformity. From May 2006 to May 2007 in a hospital, 50 cases of synovitis due to knee osteoarthritis were treated with internal and external application of Niuqinzi Decoction, and the results were satisfactory. .

The main recipe of burdock soup is: burdock 9g, silkworm 9g, white peony 9g, live alone 6g, gentiana 5g, white peony root 5g, Pinellia 6g, mulberry branch 9g.

Dosage on the medicine is used, and the decocting room is used for processing. The drug is soaked for half an hour, and then it is decocted for 30 minutes under the high temperature and pressure of the decocting machine. The liquid is filled into bags and each bag is 150 ml. Orally twice a day, 1 bag each morning and evening. Each 7 capsules of Chinese medicine dregs are brought back by the patient and the dregs are divided into 3 portions. When used in the microwave heating and then on a special cloth bag (length 28cm, width 16cm) tied in the knee, the temperature should not be too high, so as not to burn the skin, to be cooled after taking off the bag, the next time when re-warming. 1 dose of dregs is used for 2 days and 3 can be used for 1 week. Take 1 month as a course of treatment, generally treat 1 to 2 courses of treatment.

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