Scientists find new mechanisms to inhibit stem cells in triple-negative breast cancer
Scientists find new mechanisms to inhibit stem cells in triple-negative breast cancer April 27, 2017 Source: Chinese Journal of Science Recently, the research team of Kunming Institute of Zoology of the Chinese Academy of Sciences has elucidated the new regulatory mechanism of KLF5 and the new mechanism of metformin inhibiting triple-negative breast cancer stem cells, providing a theoretical basis for the clinical treatment of triple-negative breast cancer with metformin, and the development of targeted drugs for triple-negative breast cancer. Provide new targets. The research results were published in Nature-Cell Discovery. Tumor stem cells, also known as tumor-initiating cells, are a group of cells that have self-renewal capacity in tumors and produce heterogeneous tumor cells. At present, the commonly used treatment methods in the clinic can not only have a good killing effect on cancer stem cells, but also enrich the tumor stem cells to some extent, thereby causing drug resistance and recurrence. Triple-negative breast cancer is rich in cancer stem cells. Therefore, in-depth study of triple-negative breast cancer stem cells has found that effective targeted drugs can well control the development of triple-negative breast cancer. Researchers have found that metformin, a first-line drug that treats diabetes and has less side effects, can reduce ALDH-positive breast cancer stem cell populations and inhibit microsphere formation. Further through the tumor stem cell detection standard, the limited-dilution tumor formation experiment found that metformin can significantly reduce the tumor formation and tumor proliferation ability of triple-negative breast cancer cells in animals, indicating that metformin can inhibit triple-negative breast cancer stem cells. (Reporter Guo Shuang)
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So what about the advantages of the AHD Four in One CCTV Kit?
AHD Four in One CCTV Kit is the combination of the AHD Four in One Cameras and the Digital Video Recorder. Let me introduce you the 2 parts respectively.
The AHD Four in One Camera, also called the Analog High Definition Camera, one type of the analog camera, contains 4 video formats, and they are AHD,TVI,CVI,and CVBS respectively. The AHD Four in One Camera can transmit the ultra-long distant (500 meters) high-definition analog signal(resolution above 720P is High Definition, also called the HD ) via the ordinary video cable or the 75-5 coaxial cable.The AHD Four in One Camera adopts the advanced Y/C signal separation and analog filtering technology, which can effectively reduce color noise in the high-frequency area and improve the image restoration. Besides, compared with the traditional analog high-definition camera, the image resolution of the AHD Four in One Camera has a great improvement and the highest definition can reach up to the equal level to the network HD 1080P.
The Digital Video Recorder, also called the DVR, is the video storage device(a computer system for image storage and processing) via the hard disk recording. The Digital Video Recorder has the functions of long-term image recording, voice recording, remote monitoring and control of images/voices. In terms of the image processing, image storage, retrieval, backup, network transmission, and remote control, the Digital Video Recorder is the far superior to the analog monitoring equipment because of the adoption of the digital recording technology.
The Digital Video Recorder represents the developing direction of the TV monitoring system, and it is also the first choice for the TV monitoring system in this market.
What about the disadvantages for the AHD Four in One CCTV kit?
The AHD Four in One CCTV Kit is wired and it is not so convienient as the Wireless CCTV Kit in some applications, but the AHD Four in One CCTV Kit is stable and cheap in some degree.
Therefore, we should choose the suitable CCTV Kit according to our demand.