Fruit and medicine, can not help but with the exclusion zone

Hubei Daily News reporter Chen Yu

柚子

Nowadays, it is the time when grapefruit is mass-marketed. Delicious and succulent grapefruit is a fruit that many people love to eat. However, Liu’s mother, who lives in Wuchang Dingziqiao, recently had a false alarm: eating a grapefruit out of control of blood pressure.

Liu Po ​​had been suffering from high blood pressure for many years. She always insisted on taking medications on time, but also paid attention to diet, and her blood pressure was well controlled. "Listening to neighbors said grapefruit is rich in vitamin C and various types of insulin and other ingredients that can help lower blood fat and blood sugar. I would buy yuzu from supermarkets every three to five years," Liu said.

At noon the day before yesterday, after she had eaten half the grapefruit, Liu Po ​​suddenly experienced symptoms such as dizziness, nausea and palpitation, and her blood pressure suddenly dropped. After going to the hospital for examination, the doctor told her that it was because the two “good friends” of grapefruit and high blood pressure had hit their heads.

Experts from the Provincial Food and Drug Administration's Adverse Reaction Center pointed out that since grapefruit itself is rich in potassium, it has antihypertensive effect itself, and it can also increase the blood drug concentration of antihypertensive drugs. Therefore, it should be eaten during antihypertensive drugs. Grapefruit or drinking grapefruit juice, is equivalent to increasing the dose, may make blood pressure plummeted, ranging from dizziness, palpitation, fatigue, severely induced angina, myocardial infarction or stroke.

In addition to antihypertensive drugs, there are several other drugs that cannot be served with grapefruit.

Eating citrons during attenuating medications such as atorvastatin, lovastatin, and simvastatin will increase the likelihood of muscle pain and rhabdomyolysis. Severe acute renal failure may also occur; grapefruit and sedative hypnotics Services may increase the likelihood of causing dizziness and drowsiness. Attention should be given to high-altitude workers and drivers during drug use. Citrons and contraceptives may cause contraceptive failure; grapefruit and anti-allergic drugs may cause dizziness and heart palpitations. Symptoms such as arrhythmias; grapefruit and immunosuppressive agents served together, may increase liver and kidney toxicity, and have the risk of inducing tumors.

In addition to grapefruit, there are also several fruits that need attention to avoid the "forbidden zone." Among them, oranges, bananas, and unpeeled apples should be especially noticed.

Oranges: Studies have found that taking pravastatin (a hypolipidemic drug) while eating oranges and oranges can increase the ability of the liver to take drugs and increase its bioavailability. Muscular soreness and fatigue may occur.


Bananas: Patients with Parkinson's disease cannot swallow levodopa (such as metoprolol and sulfasine) with freshly squeezed banana juice, nor do they recommend taking pills while eating at the same time to avoid reducing efficacy.

Apple: Peeled apples contain 0.4 micrograms of vitamin K per 100 grams, and unpeeled apples contain 60 micrograms of vitamin K per 100 grams. For adults receiving warfarin (anticoagulant) treatment, eating unpeeled apples will greatly increase the intake of vitamin K, resulting in a decrease in the anticoagulant effect of warfarin, which may lead to thrombosis.

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