Recently, Oxford University's Wellcome Trust Centre for Human Genetics and Genomics plc, a leading UK company in genomic analysis, announced the first use of a handheld nanopore sequencer to complete multiple human genomes. Sequencing and analysis. The results, announced at the Oxford Nanopore Industry Conference in New York, marked a breakthrough in sequencing technology and opened the door to large-scale use of nanopore sequencing technology.

Nanopore technology is a new technology emerging in the field of gene sequencing in recent years. Its main principle is to drive single-stranded DNA molecules through electrophoresis through a small hole with a diameter of only 1 nanometer. When different nucleotides pass through the nanopore. Because of its unique structure, a specific change is made to the current through the nanopore. By capturing and analyzing this current change, the sequence of nucleotides can be recorded. Since the nanopore allows only nucleotides on the DNA molecule to pass one by one, the continuity and accuracy of sequencing are very high. And sequencing can be performed without amplification or labeling of DNA, which is expected to reduce the cost of sequencing.

Nanopore Sequencing Technology (Source: MIT Review)

This latest achievement from Oxford University and Genomics plc will likely bring significant changes to the DNA sequencing industry. They used the MinION sequencer from the British biotechnology company Oxford Nanopore Technologies. MinION is a chocolate bar-sized handheld sequencer that connects to a computer via a USB port and costs only $1,000. Nanopore sequencing technology was invented two years ago, but it was only used to sequence smaller genomes such as bacteria or viruses. Recent technology upgrades have enabled researchers to simultaneously sequence multiple human genomes using multiple MinION sequencers.

MinION Sequencer (Source: bio-itworld)

A major advantage of nanopore sequencing technology is that it can continuously read much longer DNA sequences than the prior art, which is particularly important in human genome sequencing. It allows researchers to obtain high-quality data in areas of the genome that are important for biological significance, and it is also easier to detect large-scale structural changes in a single genome. In this trial, the team at Oxford University and Genomics plc first completed the sequencing of a human standard sample, NA12878, and then completed the sequencing of a patient at the Oxford Biomedical Research Center.

Waterproof Dry Robe Poncho

Good quality Waterproof dry robe poncho, long sleeve waterproof dry robe, beach dry robe, surf Change Robe, hi vis safety jacket, bomber jacket , reflective vest, safety rain pants and etc.

Waterproof Dry Robe Poncho,Long Sleeve Waterproof Dry Robe,Beach Dry Robe,Surf Change Robe

Suzhou Golden Gamrnet MFG Co.,Ltd , https://www.suzhoumfg.com