Ginkgo biloba extract has a complex chemical composition, and the main active ingredients are flavonoids and terpenoid lactones. At present, the internationally recognized content of ginkgo leaf preparations is flavonoids ≥ 24% and ginkgolides ≥ 6%. Modern pharmacological studies have shown that flavonoid glycosides can effectively remove toxic peroxygen free radicals in the body, which can lower blood lipids, promote blood circulation and brain metabolism. Ginkgo biloba lactones not only have dilated coronary blood vessels, increase blood flow, improve brain In addition to nutrition and antibacterial effects, it also has a strong inhibitory effect on platelet activating factor, so it has high medicinal and economic value.


The commonly used ginkgo extraction methods include organic solvent extraction, water extraction and supercritical extraction. These methods not only waste organic solvent conditions but also have low extraction yield. Now ultrasonic extraction can solve these problems quickly and effectively. Ultrasonic extraction has the advantages of simple equipment, convenient extraction, high efficiency, energy saving and environmental protection, and has been widely used in the extraction of plant active ingredients.

Research institutions have now developed the best ultrasonic extraction method for Ginkgo biloba extract. The method is as follows:

Results: The optimal extraction conditions were ultrasonic power 100%, ultrasonic time 45 min, liquid-solid ratio 12:1, solvent concentration 30%, and extraction times 2 times. Analysis and analysis showed that the extraction rate of total flavonoids was 1.2%, and the extraction rate of ultrasonic extraction was about 1.5 times higher than that of solvent method.

Conclusion: Ultrasonic extraction of Ginkgo biloba leaves has the advantages of low cost, high recovery rate and less residual organic solvent.

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