Focus on how technology giants such as IBM, Google, Apple, and Facebook enter the genetic field

At this time, if I don't want to describe how much fire detection is a word, I think that the second is that the word is poor - there are more than 600 companies in China's genetic field. After the technology giants such as Apple, IBM, Google, and Microsoft extended their business to the medical field, they also rushed to the genetic testing market. Today, let's take a look at the layout of several technology giants in the genetic market.

I. IBM: The technology giant that does not research biotechnology is not a good IT company.

IBM is the world's largest information technology and business solutions company with headquarters in New York. Thomas, 1924. Watson founded IBM, which was founded as a business typewriter, and later turned into a word processor, and gradually grew into a global technology giant.

IBM first came into contact with the medical field, actually starting in the 1940s. The earliest medical move was to develop a remote control typewriter keyboard for disabled people.

Back to the topic, in fact, IBM began to lay out the genetic field in 2001. In June 2010, IBM announced the implementation of 64-bit Java(R) technology into its AIX(R) UNIX operating system. This means that AIX system performance will achieve a qualitative leap, far beyond systems such as Sun Solaris and Hewlett-Packard HP-UX. More importantly, this technology demonstrates the potential of application in the life sciences as a search tool for human genome data.

In September of the following year, IBM's outstanding genes in the IT field attracted two biotech companies, Celera Genomics and Applied Biosystems, which will select IBM's supercomputers to serve their drug discovery and knowledge businesses. Applied is also expected to further collaborate with IBM to accelerate its drug discovery and potential development progress with IBM's advanced information technology. Specific projects include joint research on solutions to problem-solving, development of new drug targets, and collaborative promotion of new life science solutions.

聚焦IBM、谷歌、苹果、Facebook等科技巨头如何入局基因领域

In July 2010, IBM announced a partnership with the University of Missouri-Kansa (MU) to leverage IBM's high-performance computing platform to create the first regional-level development genomics research cloud environment for MU. The cloud environment supports access through public and private networks, and services are storable. The IBM-MU Genomics Cloud will be able to share and collaborate on scientific discoveries across a wide range of areas to help promote MU bioinformatics research projects.

In the early years, there were still many flaws in the generation of sequencing technology. In particular, the cost of sequencing of the sky-high price limits the possibility of popularization of sequencing technology. During this period, IBM also uses its IT technology to provide data service support for scientific research institutions. After slowly becoming familiar with the genetic field, IBM began to accumulate power.

In 2011, IBM worked with Roche, Arizona State University, and Columbia University to develop next-generation DNA sequencing technology. IBM has played an important role in this joint mission. Its research and development of DNA transistor technology can control the slow movement of DNA molecules through the nanopores of silicon crystal chips, helping to decode the base sequence of DNA molecules through nanopores.

Since then, IBM has used its innate advantages in the IT field, frequently collaborating with gene sequencing and bioinformatics companies to gradually expand its layout in the genetic field.

In April 2013, IBM and CLC Bio reached a partnership to provide customers with an all-inclusive next-generation sequencing data analysis solution. CLC Bio is a Danish bioinformatics analysis and visualization platform that researches and provides a wide range of world-class bioinformatics solutions based on world-leading algorithm calculations. The company was acquired by QIAGEN in October 2013.

In March 2014, IBM announced a partnership with the New York Genomics Center to advance the use of genomics in medicine. Based on IBM's extensive genomic data and related literature reserves, it will provide clinicians with more comprehensive information to help doctors analyze and interpret patient genetic data and develop more personalized treatment options. In addition, it can help scientists understand the genetic sequence differences between tumors and normal people. This is also the first time Watson has applied to genomics research.

After 2014, the cost of gene sequencing has been greatly reduced. IBM saw the application of genomics in clinical medicine. I have to say that IBM is a smart company and has been exploring the clinical application of genomics since 2014.

In October 2014, IBM announced a partnership with the Cleveland Clinic to advance the use of the genome in medicine. Based on IBM's technical support, the Cleveland Clinic will unlock the prospects for genome sequencing and medical data in medical applications, helping oncologists discover new cancer treatment options and provide patients with more treatment options. In 2015, he collaborated with Boston Children's Hospital to promote research on rare diseases in children.

In October 2016, IBM launched Watson for Genomics in conjunction with Quest Diagnostics, the world's leading clinical diagnostics company, and the Precision Medicine and Tumor Genome Sequencing, to help American oncologists develop personalized medicine. Watson for Genomics will screen anonymous patient data to provide information for scientific organizations around the world that can advance research and uncover hidden patterns behind drug-resistant cancer. The Memorial Sloan Kettering Cancer Center (MSK) will provide data support for Watson, providing cancer patients with a sophisticated treatment option.

Quest Diagnostics is a leader in gene sequencing and oncology diagnostics, serving more than half of doctors and hospitals nationwide, and occupies 70% of the cancer care market in the United States. The move marks Watson's first nationwide application of Watson for Genomics.

During the 2017 Morgan Conference, IBM again aligned itself with the global sequencing giant Illumina. The two companies will collaborate on the interpretation of genomic data. IBM-Illumina provides a perfect sequencing solution for general hospitals: sequencing is limited to 170 tumor gene catalogues, which include all targets that have been approved and are undergoing trials; IBM Waston will receive data Quickly analyze the data and inform hospitals and patients about the types of genetic mutations and therapeutic drugs. Steve Harvey, vice president of Watson Health, said the alliance's goal is to allow DNA to be sequenced in general hospitals, which could benefit 20,000 Americans.

All of the above are strategic arrangements through cooperation, but this does not mean that IBM has no independent exploration capabilities. In August 2016, IBM announced an ongoing research program to help doctors achieve early detection of cancer and track treatment outcomes in real time. This also means that IBM officially entered the field of liquid biopsy. It is understood that liquid biopsy is a big market of billions of dollars, including many giant companies such as Illumina, and why an IT company wants to enter the market with such high-profile? According to the company, IBM has a strong background in microelectronics and nanotechnology, and they believe this is the right thing.

In fact, this is not IBM's first exploration in biotechnology. As early as 2006, IBM announced the discovery of its researchers sharing in DNA mode. In 2008, IBM also participated in the Cocoa Genomic Sequence Research Project with Mars.

With the main line, IBM perfectly explains what a technology giant that doesn't research biotechnology is not a good information technology company. IBM's IT attributes are obvious, so the company relies on its innate advantages, as well as the IT needs of biological companies, to first familiarize themselves with the market and gain a foothold. Although it may not be dominant in BT technology, relying on the blessing of IT technology, IBM's entry into the BT sector will be much easier than other newcomers. The reason why IBM can enter the genetic field more smoothly is because of the fate of the combination of IT and BT, on the other hand, it is also inseparable from the company's own courage to explore the genes and sensitive market smell.

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