Release date: 2018-05-02

The US research team used 3D printing technology to develop a special type of denture containing microcapsules that regularly release antifungal drugs, which can effectively prevent oral infections in dentures.

A recent study published in the journal Materials Newsletter shows that this 3D printed denture uses polymethyl methacrylate, a material commonly used in the manufacture of clinical prostheses such as dentures and artificial joints.

The researchers placed permeable, biodegradable microspheres in the material and injected the antifungal drug amphotericin B into the microspheres, which spread through a porous layer into the denture wearer's mouth. Unlike traditional denture disinfection methods, patients can be disinfected while wearing dentures.

After testing, the researchers found that the microspheres can release the drug continuously, and can effectively inhibit the colonization of Candida albicans in the oral cavity, and the 3D printed dentures have the same pressure resistance and impact resistance as traditional dentures.

Pravin Alani, a senior author of the paper and assistant professor of the Department of Oral Biology at the School of Dentistry at the State University of New York at Buffalo, said the technology allows clinicians to customize dentures for patients by the dental chair. The traditional production process takes several days. Produced in a few weeks.

The research team said that it will further study the use of glass fiber and carbon nanotubes to strengthen the strength of this denture. In addition, this technology can be applied to a variety of clinical tools such as splints, stents and prostheses.

Source: Xinhuanet

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