In recent years, "Magic Clip" CRISPR has become a hot genetic editing tool in the life sciences. Last week, the GEN website published a report entitled "User-Friendly Technology the Key to Gene-Editing's Bloom", which analyzed the genetic editing market in recent years. According to the article, in 2016, the gene editing market will reach 608 million US dollars.

Gene editing techniques (including ZFNs, TALENs, and CRISPR-Cas9) have commercial applications in many areas, such as developing human disease treatment options, developing new varieties of plants and animals, and improving animal models for research. Currently, some genetic editing-based projects are undergoing different stages of development, including HIV/AIDS therapy, herbicide-tolerant canola, acute lymphoblastic leukemia therapy, genetically modified soybeans, genetically modified Bama pigs, and rodent models.

Key players in the gene editing technology market include MilliporeSigma, Thermo Fisher, Dharmacon, GeneCopoeia, GenScript, Horizon Discovery Group, OriGene, Transposagen, and ToolGen.

According to Kalorama Information, genetic editing tools, reagents, services, models and other related supply markets will reach $608 million in 2016. In 2014, this market was $234 million. With the development of new applications and related projects, this market is expected to continue to grow rapidly in the next five years. Among them, the increase in the use of genetic editing in the development of disease treatment programs and agriculture is one of the drivers of growth in this market.

Gene Editing Market 2014–2016. (tools, reagents, services, and supplies)

The development of disease treatment programs based on gene editing technology has attracted the attention of many companies, and related projects have also received a large amount of investment. Companies including Bayer, Biogen, Juno Therapeutics, Novartis, Pfizer, Regeneron Pharmaceuticals are involved. Some companies invest by way, while others work with small companies. Here are some examples:

Bayer & CRISPR Therapeutics

On May 17, according to Bayer's official website, the company signed a patent license agreement with ERS Genomics. ERS Genomics has a patent for the CRISPR-Cas9 foundation from CRISPR pioneer Emmanuelle Charpentier. It is worth noting that this is actually the second deal between Bayer and Charpentier. In December last year, Bayer and CRISPR Therapeutics (a company co-founded by Charpentier) announced the establishment of a joint venture focused on the development and commercialization of new treatments for blood diseases, blindness and congenital heart disease.

Last month, following Editas and Intellia, CRISPR Therapeutics announced an IPO to land on the Nasdaq market. The company issued 4 million shares at a price of $14 per share, raising a total of $56 million. It is reported that Bayer has purchased 2.5 million shares in the IPO. In addition to Bayer, CRISPR Therapeutics has also been supported by giants such as New Base, GSK and Vertex.

Mottled Waxy Corn

How should I eat maize every day? We need to control the amount of corn, according to the dietary guidelines, the amount of staple food we use in our lives should be controlled at 250 grams to 400 grams, and the ratio of coarse to fine grains is one to three or one to four, which simply means that about 130 grams of corn can be used every day, in addition to the appropriate reduction in the intake of staple food, let's say half a bowl of rice or a steamed bun, so as to avoid excessive calorie intake in our bodies.

It is also important to note that when eating corn, it is advisable to eat the whole cob together to better control our blood sugar. If corn is processed into corn juice or cornmeal food, the nutrients inside are often lost and what remains is basically sugar, which is often higher on the glycemic index and more likely to lead to a rise in blood sugar, for example, the glycemic index of ordinary corn is only 55, but with foods such as cornmeal, the glycemic index often reaches 68, so it is important to eat the right corn.

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