China Factory 99% Purity of Flumazenil Powder CAS 78755-81-4
Nootropic Supplement Drug Flumazenil 78755-81-4 White Powder for Strength Increasing
Description:
Flumazenil, an imidazobenzodiazepine, is a benzodiazepine antagonist which specifically blocks the
central effects of agents acting through the benzodiazepine receptor by competitive inhibition. In animal
experiments the effects of compounds showing no affinity for the benzodiazepine receptor, e.g.
barbiturates, ethanol, , GABA mimetics, adenosine receptor agonists and other agents were
not affected by flumazenil, but those of nonbenzodiazepine agonists of benzodiazepine receptors, such
as cyclopyrrolones (e.g. zopiclone) and triazolopyridazines were blocked.Â
Quick Details:
Chemical name: Flumazenil
MF:C15H14FN3O3
MW:303.29
CAS:78755-81-4
MOQ: 1g
Packing:10g/foil bag
Delivery time: 3~7 working days
COA:
Struscture Characteristics:
Flumazenil is a white to off-white crystalline compound with an octanol: buffer partition coefficient of 14 to 1 at pH 7.4. It is insoluble in water but slightly soluble in acidic aqueous solutions. Flumazenil injection is available as a sterile parenteral dosage form for intravenous administration. Each mL contains 0.1 mg of flumazenil compounded with 1.8 mg of methylparaben, 0.2 mg of propylparaben, 0.9% sodium chloride, 0.01% edetate disodium, and 0.01% acetic acid; the pH is adjusted to approximately 4 with hydrochloric acid and/or, if necessary,
Medical uses:
There are many complications that must be taken into consideration when used in the acute care setting.These include lowered seizure threshold, agitation, and anxiousness. Flumazenil's short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms.
Flumazenil has been effectively used to treat overdoses of non-benzodiazepine hypnotics, such as zolpidem, zaleplon and zopiclone.
It may also be effective in reducing excessive daytime sleepiness while improving vigilance in primary hypersomnias, such as idiopathic hypersomnia.
It has also been used in hepatic encephalopathy, though results have been mixed.
The onset of action is rapid and usually effects are seen within one to two minutes. The peak effect is seen at six to ten minutes. The recommended dose for adults is 200 μg every 1-2 minutes until the effect is seen, to a maximum of 3 mg per hour. It is available as a clear, colourless solution for intravenous injection, containing 500 μg in 5 mL.
Do NOT use flumazenil if:
you have been given a benzodiazepine for control of a potentially life-threatening condition (eg, increased pressure in the head, seizures)
you are experiencing side effects due to an overdose of a medicine used to treat depression
Contact your doctor or health care provider right away if any of these apply to you.
Packing:Â
1. food bag camouflage
2. change the name to ship  your parcel
3. according to your suggestion
Â
Nootropic Supplement Drug Flumazenil 78755-81-4 White Powder for Strength Increasing
Description:
Flumazenil, an imidazobenzodiazepine, is a benzodiazepine antagonist which specifically blocks the
central effects of agents acting through the benzodiazepine receptor by competitive inhibition. In animal
experiments the effects of compounds showing no affinity for the benzodiazepine receptor, e.g.
barbiturates, ethanol, , GABA mimetics, adenosine receptor agonists and other agents were
not affected by flumazenil, but those of nonbenzodiazepine agonists of benzodiazepine receptors, such
as cyclopyrrolones (e.g. zopiclone) and triazolopyridazines were blocked.Â
Quick Details:
Chemical name: Flumazenil
MF:C15H14FN3O3
MW:303.29
CAS:78755-81-4
MOQ: 1g
Packing:10g/foil bag
Delivery time: 3~7 working days
COA:
Struscture Characteristics:
Flumazenil is a white to off-white crystalline compound with an octanol: buffer partition coefficient of 14 to 1 at pH 7.4. It is insoluble in water but slightly soluble in acidic aqueous solutions. Flumazenil injection is available as a sterile parenteral dosage form for intravenous administration. Each mL contains 0.1 mg of flumazenil compounded with 1.8 mg of methylparaben, 0.2 mg of propylparaben, 0.9% sodium chloride, 0.01% edetate disodium, and 0.01% acetic acid; the pH is adjusted to approximately 4 with hydrochloric acid and/or, if necessary,
Medical uses:
There are many complications that must be taken into consideration when used in the acute care setting.These include lowered seizure threshold, agitation, and anxiousness. Flumazenil's short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms.
Flumazenil has been effectively used to treat overdoses of non-benzodiazepine hypnotics, such as zolpidem, zaleplon and zopiclone.
It may also be effective in reducing excessive daytime sleepiness while improving vigilance in primary hypersomnias, such as idiopathic hypersomnia.
It has also been used in hepatic encephalopathy, though results have been mixed.
The onset of action is rapid and usually effects are seen within one to two minutes. The peak effect is seen at six to ten minutes. The recommended dose for adults is 200 μg every 1-2 minutes until the effect is seen, to a maximum of 3 mg per hour. It is available as a clear, colourless solution for intravenous injection, containing 500 μg in 5 mL.
Do NOT use flumazenil if:
you have been given a benzodiazepine for control of a potentially life-threatening condition (eg, increased pressure in the head, seizures)
you are experiencing side effects due to an overdose of a medicine used to treat depression
Contact your doctor or health care provider right away if any of these apply to you.
Packing:Â
1. food bag camouflage
2. change the name to ship  your parcel
3. according to your suggestion
Â